Description
Milk Thistle: Milk thistle extract may support the liver by optimizing the detoxification pathways specifically phase 1. As with other bioflavonoids, silymarin can be a powerful antioxidant1, which becomes critical during the detoxification process especially after phase 1 is completed.
N-Acetyl Cysteine: NAC is an amino acid and precursor to intracellular cysteine and glutathione, both of which are integral to the detoxification pathways. Studies have demonstrated that NAC appears to exert protective effects by modulating glutathione metabolism and the biotransformation of mutagenic compounds2.
1. Feher J, Lang I, Deak G, et al. Free radicals in tissue damage in liver diseases and therapeutic approach.Tokai J Exp Clin Med 1986;11:121–34.
2. De Flora S. In vivo effects of N-acetylcysteine on glutathione metabolism and on the biotransformation of carcinogenic and/or mutagenic compounds. Carcinogenesis. 1985 Dec;6(12):1735-45.
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